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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735868
Species: Homo sapiens
RGD Object: Gene
Symbol: NQO1
Name: NAD(P)H quinone dehydrogenase 1
Acc ID: CHEBI:46666
Term: crocidolite asbestos
Definition: null
Chemical ID: MESH:D017638
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NQO1increases expressionISONqo1 (Mus musculus)6480464CTDAsbestos, Crocidolite results in increased expression of NQO1 mRNA; Asbestos, Crocidolite results in increased expression of NQO1 proteinPMID:26938529
NQO1multiple interactionsISONqo1 (Mus musculus)6480464CTDsecoisolariciresinol diglucoside promotes the reaction [Asbestos, Crocidolite results in increased expression of NQO1 mRNA]; secoisolariciresinol diglucoside promotes the reaction [Asbestos, Crocidolite results in increased expression of NQO1 protein]PMID:26938529
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