Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735868
Species: Homo sapiens
RGD Object: Gene
Symbol: NQO1
Name: NAD(P)H quinone dehydrogenase 1
Acc ID: CHEBI:30185
Term: zinc(0)
Definition: An elemental zinc that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NQO1 mRNA

PMID:16979875
multiple interactionsISORGD:104736480464CTDZinc deficiency promotes the reaction [Dietary Fats results in decreased expression of NQO1 mRNA], Zinc deficiency promotes the reaction [Dietary Fats results in decreased expression of NQO1 protein], Zinc inhibits the reaction [Dietary Fats results in decreased expression of NQO1 mRNA], Zinc inhibits the reaction [Dietary Fats results in decreased expression of NQO1 protein], Zinc promotes the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]

PMID:14998373, PMID:27370414
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.