GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | EPO | decreases response to substance | EXP | | 6480464 | CTD | EPO protein results in decreased susceptibility to Cisplatin | PMID:23077460 | EPO | increases response to substance | EXP | | 6480464 | CTD | EPO protein results in increased susceptibility to Cisplatin | PMID:23077460 | EPO | multiple interactions | EXP | | 6480464 | CTD | Cisplatin inhibits the reaction [cobaltous chloride results in increased expression of EPO mRNA]; Cisplatin inhibits the reaction [cobaltous chloride results in increased expression of EPO protein]; Cisplatin inhibits the reaction [Oxygen deficiency results in increased expression of EPO mRNA]; Cisplatin inhibits the reaction [Oxygen deficiency results in increased expression of EPO protein]; EPO protein inhibits the reaction [Cisplatin results in decreased abundance of Glutathione]; EPO protein inhibits the reaction [Cisplatin results in increased activity of CAT protein] | PMID:11090055 PMID:22013135 | EPO | affects expression | ISO | Epo (Rattus norvegicus) | 6480464 | CTD | Cisplatin affects the expression of EPO protein | PMID:20020992 | EPO | decreases response to substance | ISO | Epo (Rattus norvegicus) | 6480464 | CTD | EPO protein results in decreased susceptibility to Cisplatin | PMID:20722073 | EPO | increases expression | ISO | Epo (Rattus norvegicus) | 6480464 | CTD | Cisplatin results in increased expression of EPO protein | PMID:2206997 | | ||||||||||||||||||||||
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