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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735826
Species: Homo sapiens
RGD Object: Gene
Symbol: GAST
Name: gastrin
Acc ID: CHEBI:31767
Term: lead diacetate
Definition: A lead coordination entity in which a central lead(2+) atom is coordinated to two acetate ions.
Chemical ID: MESH:C008261
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDlead acetate results in increased expression of GAST mRNA, lead acetate results in increased expression of GAST protein

PMID:23765435
multiple interactionsEXP 6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead acetate results in increased expression of GAST mRNA], 4-((3-bromophenyl)amino)-6, 7-dimethoxyquinazoline inhibits the reaction [lead acetate results in increased expression of GAST mRNA], RTKI cpd inhibits the reaction [lead acetate results in increased expression of GAST mRNA]

PMID:23765435
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.