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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735760
Species: Homo sapiens
RGD Object: Gene
Symbol: ATF3
Name: activating transcription factor 3
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ATF3increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of ATF3 mRNAPMID:26238291
ATF3multiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] results in increased expression of ATF3 mRNAPMID:29704546
ATF3affects expressionISOAtf3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of ATF3 mRNAPMID:21570461 PMID:26377647
ATF3decreases expressionISOAtf3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of ATF3 mRNAPMID:19770486 PMID:19933214
ATF3decreases expressionISOAtf3 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of ATF3 mRNAPMID:34747641
ATF3increases expressionISOAtf3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of ATF3 mRNA; Tetrachlorodibenzodioxin results in increased expression of ATF3 proteinPMID:16891777 PMID:18467041 PMID:24058054
ATF3increases expressionISOAtf3 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of ATF3 mRNAPMID:21215274 PMID:32109520 PMID:33387578
ATF3multiple interactionsISOAtf3 (Mus musculus)6480464CTDAHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of ATF3 mRNA]PMID:16891777
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