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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735652
Species: Homo sapiens
RGD Object: Gene
Symbol: AR
Name: androgen receptor
Acc ID: CHEBI:8489
Term: propiconazole
Definition: The cyclic ketal obtained by formal condensation of 1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone with pentane-1,2-diol. A triazole fungicide, it is used commercially as a diastereoisomeric mixture on soft fruit (including apricots, peaches, nectarines, plums and prunes), nuts (including peanuts, pecans and almonds), mushrooms, and grasses grown for seeds.
Chemical ID: MESH:C045950
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ARmultiple interactionsEXP 6480464CTD[bitertanol co-treated with propiconazole co-treated with cypermethrin] inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; [propiconazole co-treated with prochloraz co-treated with tebuconazole] inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; [propiconazole co-treated with prochloraz] inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; [terbutylazine co-treated with bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion] inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; [terbutylazine co-treated with bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion] results in decreased activity of AR protein; Dihydrotestosterone inhibits the reaction [propiconazole results in increased activity of AR protein]; propiconazole inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; propiconazole inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; propiconazole inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; propiconazole inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]; propiconazole inhibits the reaction [Metribolone results in increased activity of AR protein]PMID:15064155 PMID:18324785 PMID:23871939 PMID:26602169 PMID:28728110 PMID:33049310
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