GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | AR | decreases activity | EXP | | 6480464 | CTD | cypermethrin results in decreased activity of AR protein | PMID:20410157 | AR | multiple interactions | EXP | | 6480464 | CTD | [bitertanol co-treated with propiconazole co-treated with cypermethrin] inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; [Dihydrotestosterone co-treated with cypermethrin] results in decreased expression of AR mRNA; [terbutylazine co-treated with bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion] inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; [terbutylazine co-treated with bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion] results in decreased activity of AR protein; cypermethrin inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; cypermethrin inhibits the reaction [Metribolone results in increased activity of AR protein] | PMID:16857237 PMID:17980950 PMID:18324785 PMID:23871939 | AR | decreases expression | ISO | Ar (Mus musculus) | 6480464 | CTD | cypermethrin results in decreased expression of AR mRNA; cypermethrin results in decreased expression of AR protein | PMID:24810582 | AR | decreases expression | ISO | Ar (Rattus norvegicus) | 6480464 | CTD | cypermethrin results in decreased expression of AR mRNA; cypermethrin results in decreased expression of AR protein | PMID:22147539 PMID:34794910 | AR | multiple interactions | ISO | Ar (Mus musculus) | 6480464 | CTD | cypermethrin inhibits the reaction [AR protein binds to SRC protein] | PMID:30974244 | AR | multiple interactions | ISO | Ar (Rattus norvegicus) | 6480464 | CTD | [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of AR mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of AR mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of AR mRNA | PMID:33051911 PMID:33396045 PMID:34896426 | | ||||||||||||||||||||||
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