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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735621
Species: Homo sapiens
RGD Object: Gene
Symbol: CXCL2
Name: C-X-C motif chemokine ligand 2
Acc ID: CHEBI:3374
Term: capsaicin
Definition: A capsaicinoid that has formula C18H27NO3.
Chemical ID: MESH:D002211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CXCL2increases expressionISOCxcl2 (Rattus norvegicus)6480464CTDCapsaicin results in increased expression of CXCL2 proteinPMID:22150557
CXCL2multiple interactionsISOCxcl2 (Rattus norvegicus)6480464CTD[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CXCL2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CXCL2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CXCL2 protein]PMID:22150557
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