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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735621
Species: Homo sapiens
RGD Object: Gene
Symbol: CXCL2
Name: C-X-C motif chemokine ligand 2
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CXCL2affects methylationEXP 6480464CTDBenzo(a)pyrene affects the methylation of CXCL2 3' UTRPMID:27901495
CXCL2decreases expressionEXP 6480464CTDBenzo(a)pyrene results in decreased expression of CXCL2 mRNAPMID:18247414 PMID:20106945 PMID:32234424
CXCL2increases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of CXCL2 mRNAPMID:22316170 PMID:28351761
CXCL2affects expressionISOCxcl2 (Mus musculus)6480464CTDBenzo(a)pyrene affects the expression of CXCL2 mRNAPMID:22342234
CXCL2decreases expressionISOCxcl2 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of CXCL2 mRNAPMID:19770486
CXCL2multiple interactionsISOCxcl2 (Mus musculus)6480464CTDBenzo(a)pyrene inhibits the reaction [Dextran Sulfate results in increased expression of CXCL2 mRNA]PMID:34998820
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