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GENE - TERM ANNOTATION REPORT

RGD ID: 735618
Species: Homo sapiens
RGD Object: Gene
Symbol: NOS3
Name: nitric oxide synthase 3
Acc ID: DOID:9005643
Term: Experimental Diabetes Mellitus
Definition: Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by PANCREATECTOMY.
Definition Source(s): MESH:D003921
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NOS3 ISONos3 (Mus musculus)7777108RGDprotein:decreased expression:thoracic aorta (mouse) 
NOS3 ISONos3 (Rattus norvegicus)2292100RGDprotein:increased expression:heart 
NOS3 ISONos3 (Rattus norvegicus)4892007RGD  
NOS3treatmentISONos3 (Mus musculus)7777108RGD  
NOS3treatmentISONos3 (Rattus norvegicus)13450939RGD  
NOS3 EXP 11554173CTDCTD Direct Evidence: marker/mechanismPMID:11696579 PMID:14871415 PMID:15490108 PMID:16959961 PMID:18266981 PMID:19478208 PMID:22191573 PMID:22933112
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