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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735609
Species: Mus musculus
RGD Object: Gene
Symbol: Nrg1
Name: neuregulin 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nrg1affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of NRG1 mRNAPMID:21570461 PMID:26377647
Nrg1increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of NRG1 mRNAPMID:19770486 PMID:19933214 PMID:21851831 PMID:26290441
Nrg1multiple interactionsEXP 6480464CTD2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NRG1 mRNA]PMID:21851831
Nrg1affects expressionISONrg1 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of NRG1 mRNAPMID:22298810 PMID:32109520
Nrg1decreases expressionISONRG1 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of NRG1 mRNAPMID:23152189
Nrg1increases expressionISONrg1 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of NRG1 mRNAPMID:19692669 PMID:20959002 PMID:21215274 PMID:33387578
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