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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735518
Species: Homo sapiens
RGD Object: Gene
Symbol: KCNA2
Name: potassium voltage-gated channel subfamily A member 2
Acc ID: CHEBI:7590
Term: nitrofen
Definition: An organic molecular entity that has formula C12H7Cl2NO3.
Chemical ID: MESH:C007350
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KCNA2decreases expressionISOKcna2 (Rattus norvegicus)6480464CTDnitrofen results in decreased expression of KCNA2 mRNA; nitrofen results in decreased expression of KCNA2 proteinPMID:15088113
KCNA2multiple interactionsISOKcna2 (Rattus norvegicus)6480464CTDDexamethasone inhibits the reaction [nitrofen results in decreased expression of KCNA2 mRNA]; Dexamethasone inhibits the reaction [nitrofen results in decreased expression of KCNA2 protein]PMID:15088113
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