GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NFKBIA | increases expression | EXP | | 6480464 | CTD | Benzo(a)pyrene results in increased expression of NFKBIA mRNA | PMID:16269432 PMID:26238291 | NFKBIA | decreases expression | ISO | Nfkbia (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of NFKBIA mRNA | PMID:21715664 | NFKBIA | decreases expression | ISO | Nfkbia (Rattus norvegicus) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of NFKBIA protein | PMID:34999049 | NFKBIA | increases expression | ISO | Nfkbia (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of NFKBIA mRNA | PMID:21569818 PMID:22228805 PMID:27195522 | NFKBIA | multiple interactions | ISO | Nfkbia (Rattus norvegicus) | 6480464 | CTD | Benzo(a)pyrene promotes the reaction [TNF protein results in increased degradation of NFKBIA protein]; Benzo(a)pyrene promotes the reaction [TNF protein results in increased expression of NFKBIA mRNA]; IL27 protein inhibits the reaction [Benzo(a)pyrene results in decreased expression of NFKBIA protein] | PMID:21745554 PMID:34999049 | |
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