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GENE - TERM ANNOTATION REPORT

RGD ID: 735430
Species: Homo sapiens
RGD Object: Gene
Symbol: IL1R1
Name: interleukin 1 receptor type 1
Acc ID: GO:0070498
Term: interleukin-1-mediated signaling pathway
Definition: The series of molecular signals initiated by interleukin-1 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Definition Source(s): GOC:BHF, GOC:mah, GOC:signaling
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL1R1 ISOIl1r1 (Rattus norvegicus)9068941RGD PMID:20967881 REF_RGD_ID:5130945
IL1R1involved_inIDA 150520179BHF-UCL PMID:10383454 PMID:2950091

PMID:10383454 PMID:2950091
IL1R1involved_inIEAUniProtKB:P13504 or ensembl:ENSMUSP00000027241150520179Ensembl GO_REF:0000107
IL1R1involved_inIBAMGI:96545 or PANTHER:PTN000223712 or Il1r1 (Rattus norvegicus) or UniProtKB:P14778150520179GO_Central GO_REF:0000033
IL1R1involved_inIEAGO:0004909150520179GOC GO_REF:0000108
IL1R1involved_inIEAPANTHER:PTHR11890:SF26150520179TreeGrafter GO_REF:0000118
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