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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735413
Species: Homo sapiens
RGD Object: Gene
Symbol: STAR
Name: steroidogenic acute regulatory protein
Acc ID: CHEBI:34795
Term: 3-isobutyl-1-methyl-7H-xanthine
Definition: A 3-isobutyl-1-methylxanthine that has formula C10H14N4O2.
Chemical ID: MESH:D015056
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
STARmultiple interactionsEXP 6480464CTD1-Methyl-3-isobutylxanthine inhibits the reaction [Atrazine inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]]; 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]]; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of STAR mRNAPMID:28628672 PMID:28859905 PMID:30951242
STARmultiple interactionsISOStar (Rattus norvegicus)6480464CTD1-Methyl-3-isobutylxanthine promotes the reaction [FSHB protein results in increased expression of STAR mRNA]PMID:25253736
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