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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735389
Species: Homo sapiens
RGD Object: Gene
Symbol: BBC3
Name: BCL2 binding component 3
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BBC3multiple interactionsEXP 6480464CTD[Glucose co-treated with Deferoxamine] results in increased expression of BBC3 mRNA; [Palmitic Acid co-treated with Glucose] results in increased expression of BBC3 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BBC3 mRNA]; SIRT1 protein mutant form inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased expression of BBC3 mRNA]PMID:24451382 PMID:33962019
BBC3multiple interactionsISOBbc3 (Mus musculus)6480464CTD[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BBC3 protein modified form; SIRT7 protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BBC3 protein]PMID:28675767
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