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GENE - TERM ANNOTATION REPORT

RGD ID: 735341
Species: Homo sapiens
RGD Object: Gene
Symbol: CDKN1A
Name: cyclin dependent kinase inhibitor 1A
Acc ID: DOID:11555
Term: Fuchs' endothelial dystrophy
Definition: A corneal dystrophy characterized by accumulation of focal outgrowths (guttae) and thickening of Descemet's membrane, leading to corneal edema and loss of vision. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Fuchs%27_dystrophy "DO" "DO", http://ghr.nlm.nih.gov/condition/fuchs-endothelial-dystrophy "DO" "DO", http://rarediseases.info.nih.gov/gard/10018/corneal-dystrophy-fuchs-endothelial-1/resources/1 "DO" "DO", http://www.mayoclinic.org/diseases-conditions/fuchs-dystrophy/basics/definition/con-20023893?_ga=1.163328703.2017809229.1415219956 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CDKN1A IEP 8661808RGDprotein:increased expression:nucleus: 
CDKN1A ISORGD:7329118661808RGDmRNA,protein:increased expression:cornea,nucleus: 
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