Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735341
Species: Homo sapiens
RGD Object: Gene
Symbol: CDKN1A
Name: cyclin dependent kinase inhibitor 1A
Acc ID: CHEBI:48843
Term: disodium selenite
Definition: An inorganic sodium salt composed of sodium and selenite ions in a 2:1 ratio.
Chemical ID: MESH:D018038
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CDKN1Aincreases expressionEXP 6480464CTDSodium Selenite results in increased expression of CDKN1A mRNA; Sodium Selenite results in increased expression of CDKN1A proteinPMID:24383545 PMID:25204997
CDKN1Amultiple interactionsEXP 6480464CTD[Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in increased expression of CDKN1A mRNA; [Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in increased expression of CDKN1A protein; Sodium Selenite inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CDKN1A protein]PMID:21515331 PMID:28757135
Go Back to source page   Continue to Ontology report