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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735341
Species: Homo sapiens
RGD Object: Gene
Symbol: CDKN1A
Name: cyclin dependent kinase inhibitor 1A
Acc ID: CHEBI:34757
Term: fenitrothion
Definition: An organic thiophosphate that is O,O-dimethyl O-phenyl phosphorothioate substituted by a methyl group at position 3 and a nitro group at position 4.
Chemical ID: MESH:D005278
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CDKN1Aincreases expressionISOCdkn1a (Rattus norvegicus)6480464CTDFenitrothion results in increased expression of CDKN1A mRNAPMID:33393722
CDKN1Amultiple interactionsISOCdkn1a (Rattus norvegicus)6480464CTD[Vehicle Emissions results in increased abundance of Particulate Matter] promotes the reaction [Fenitrothion results in increased expression of CDKN1A mRNA]; Fenitrothion promotes the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of CDKN1A mRNA]; Plant Preparations inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] promotes the reaction [Fenitrothion results in increased expression of CDKN1A mRNA]]; Plant Preparations inhibits the reaction [Fenitrothion promotes the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of CDKN1A mRNA]]; Plant Preparations inhibits the reaction [Fenitrothion results in increased expression of CDKN1A mRNA]PMID:33393722
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