GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CDKN1A | affects expression | EXP | | 6480464 | CTD | bisphenol A affects the expression of CDKN1A mRNA | PMID:22307313 PMID:30903817 | CDKN1A | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of CDKN1A; bisphenol A results in decreased expression of CDKN1A mRNA; bisphenol A results in decreased expression of CDKN1A protein | PMID:16474171 PMID:21277958 PMID:23222814 PMID:23229410 PMID:27998958 PMID:29330934 PMID:36982678 | CDKN1A | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of CDKN1A mRNA; bisphenol A results in increased expression of CDKN1A protein | PMID:29383186 PMID:31470548 | CDKN1A | multiple interactions | EXP | | 6480464 | CTD | [bisphenol A co-treated with cylindrospermopsin] results in increased expression of CDKN1A mRNA; [bisphenol A co-treated with Quercetin metabolite] results in increased expression of CDKN1A mRNA; [naringenin co-treated with bisphenol A] results in increased expression of CDKN1A mRNA; [naringenin metabolite co-treated with bisphenol A] results in increased expression of CDKN1A mRNA; bisphenol A affects the reaction [Doxorubicin affects the expression of CDKN1A mRNA]; bisphenol A inhibits the reaction [Doxorubicin results in increased expression of CDKN1A mRNA]; Curcumin inhibits the reaction [bisphenol A results in decreased expression of CDKN1A protein]; Genistein inhibits the reaction [bisphenol A results in decreased expression of CDKN1A]; Melatonin inhibits the reaction [bisphenol A results in decreased expression of CDKN1A protein] | PMID:23222814 PMID:23229410 PMID:26320837 PMID:29330934 PMID:31470548 PMID:32244372 PMID:36235125 PMID:36982678 | CDKN1A | affects expression | ISO | Cdkn1a (Rattus norvegicus) | 6480464 | CTD | bisphenol A affects the expression of CDKN1A mRNA | PMID:25181051 PMID:32145629 | CDKN1A | decreases expression | ISO | Cdkn1a (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in decreased expression of CDKN1A mRNA; bisphenol A results in decreased expression of CDKN1A protein | PMID:24884420 PMID:27178563 PMID:33296240 PMID:34947998 PMID:35192832 | CDKN1A | increases expression | ISO | Cdkn1a (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased expression of CDKN1A protein | PMID:24884420 | CDKN1A | increases expression | ISO | Cdkn1a (Mus musculus) | 6480464 | CTD | bisphenol A results in increased expression of CDKN1A mRNA | PMID:20826375 PMID:33221593 PMID:35219798 | CDKN1A | multiple interactions | ISO | Cdkn1a (Rattus norvegicus) | 6480464 | CTD | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of CDKN1A mRNA; [bisphenol A co-treated with Estradiol] results in increased expression of CDKN1A mRNA; Genistein inhibits the reaction [bisphenol A results in decreased expression of CDKN1A protein]; Genistein inhibits the reaction [bisphenol A results in increased expression of CDKN1A protein] | PMID:24884420 PMID:26496021 PMID:36041667 | |
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