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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735341
Species: Homo sapiens
RGD Object: Gene
Symbol: CDKN1A
Name: cyclin dependent kinase inhibitor 1A
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CDKN1Aaffects expressionISOCdkn1a (Mus musculus)6480464CTDpirinixic acid affects the expression of CDKN1A mRNAPMID:17950772
CDKN1Aincreases expressionISOCdkn1a (Rattus norvegicus)6480464CTDpirinixic acid results in increased expression of CDKN1A mRNAPMID:15890375
CDKN1Aincreases expressionISOCdkn1a (Mus musculus)6480464CTDpirinixic acid results in increased expression of CDKN1A mRNAPMID:16985257 PMID:18301758 PMID:18445702 PMID:18467677 PMID:20059764 PMID:20813756 PMID:23811191
CDKN1Amultiple interactionsISOCdkn1a (Mus musculus)6480464CTD[pirinixic acid co-treated with PPARA] results in increased expression of CDKN1A mRNA; PPARA protein promotes the reaction [pirinixic acid results in increased expression of CDKN1A mRNA]PMID:18467677 PMID:20059764 PMID:20813756
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