GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CDKN1A | increases expression | EXP | | 6480464 | CTD | Oxygen deficiency results in increased expression of CDKN1A mRNA; Oxygen deficiency results in increased expression of CDKN1A protein | PMID:10951577 PMID:19958256 PMID:25596134 | CDKN1A | multiple interactions | EXP | | 6480464 | CTD | 4'-O-methylalpinumisoflavone inhibits the reaction [Oxygen deficiency results in increased expression of CDKN1A mRNA]; [eprenetapopt co-treated with Cisplatin co-treated with Oxygen deficiency] results in increased expression of CDKN1A mRNA; [Oxygen deficiency co-treated with Cisplatin] results in increased expression of CDKN1A mRNA; HIF1A protein affects the reaction [Oxygen deficiency results in increased expression of CDKN1A mRNA]; HIF1A protein affects the reaction [Oxygen deficiency results in increased expression of CDKN1A protein]; Oxygen affects the reaction [AHR protein results in decreased expression of CDKN1A mRNA]; Rotenone inhibits the reaction [Oxygen deficiency results in increased expression of CDKN1A mRNA]; TP53 protein affects the reaction [[Oxygen deficiency co-treated with Cisplatin] results in increased expression of CDKN1A mRNA] | PMID:19091749 PMID:19958256 PMID:27103661 PMID:29690507 | CDKN1A | affects expression | ISO | Cdkn1a (Mus musculus) | 6480464 | CTD | Oxygen deficiency affects the expression of CDKN1A mRNA | PMID:17193925 | CDKN1A | multiple interactions | ISO | Cdkn1a (Rattus norvegicus) | 6480464 | CTD | [Valproic Acid co-treated with Oxygen deficiency] results in increased expression of CDKN1A protein; [vorinostat co-treated with Oxygen deficiency] results in increased expression of CDKN1A protein | PMID:22711276 | CDKN1A | multiple interactions | ISO | Cdkn1a (Mus musculus) | 6480464 | CTD | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of CDKN1A mRNA | PMID:30529165 | | ||||||||||||||||||||||
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