GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Akt1 | decreases activity | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | Gallic Acid results in decreased activity of AKT1 protein | PMID:22387266 | Akt1 | decreases phosphorylation | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | Gallic Acid results in decreased phosphorylation of AKT1 protein | PMID:23153558 PMID:26530725 | Akt1 | multiple interactions | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein]]; [Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein]; [MAP2K1 protein modified form co-treated with AKT1 protein modified form] inhibits the reaction [Gallic Acid inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]; [MAP2K1 protein modified form co-treated with AKT1 protein modified form] inhibits the reaction [Gallic Acid inhibits the reaction [EGF protein results in increased phosphorylation of JUN protein]]; [MAP2K1 protein modified form co-treated with AKT1 protein modified form] inhibits the reaction [Gallic Acid inhibits the reaction [EGF protein results in increased phosphorylation of RELA protein]]; AKT1 protein inhibits the reaction [Gallic Acid results in decreased expression of HIF1A mRNA]; AKT1 protein inhibits the reaction [Gallic Acid results in decreased expression of VEGFA mRNA]; BMAL1 protein affects the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein]]; Gallic Acid inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]; RHOB mutant form inhibits the reaction [Gallic Acid results in decreased phosphorylation of AKT1 protein]; SRC protein modified form inhibits the reaction [Gallic Acid inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]] | PMID:23153558 PMID:26530725 PMID:27087131 PMID:29061316 | | ||||||||||||||||||||||
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