GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Akt1 | multiple interactions | EXP | | 6480464 | CTD | Luteolin inhibits the reaction [Antimycin A results in decreased activity of AKT1 protein]; Luteolin inhibits the reaction [INS1 protein results in increased activity of AKT1 protein]; Luteolin inhibits the reaction [Lipopolysaccharides results in decreased expression of AKT1 mRNA]; Luteolin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of AKT1 protein] | PMID:18591783 PMID:18720166 PMID:21782929 PMID:37379125 | Akt1 | decreases expression | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | Luteolin results in decreased expression of AKT1 protein | PMID:22926442 | Akt1 | decreases phosphorylation | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | Luteolin results in decreased phosphorylation of AKT1 protein | PMID:19344998 PMID:38230768 | Akt1 | increases phosphorylation | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | Luteolin results in increased phosphorylation of AKT1 protein | PMID:27474067 | Akt1 | multiple interactions | ISO | Akt1 (Rattus norvegicus) | 6480464 | CTD | [Luteolin co-treated with Hydrogen Peroxide] results in increased expression of AKT1 protein; Luteolin inhibits the reaction [lipoteichoic acid results in increased phosphorylation of AKT1 protein]; Luteolin inhibits the reaction [Methamphetamine results in increased phosphorylation of AKT1 protein] | PMID:20685402 PMID:27525270 PMID:32035215 | Akt1 | multiple interactions | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | Luteolin inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of AKT1 protein]; Luteolin inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]; Luteolin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of AKT1 protein] | PMID:20153296 PMID:22926442 PMID:25448439 | |
Go Back to source page | Continue to Ontology report |