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GENE - TERM ANNOTATION REPORT

RGD ID: 735230
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Washc2c
Name: WASH complex subunit 2C
Acc ID: GO:0071203
Term: WASH complex
Definition: A protein complex that localizes at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization. In human, the WASH complex is composed of F-actin-capping protein subunits alpha and beta, WASH1, FAM21, KIAA1033, KIAA0196 and CCDC53.
Definition Source(s): GOC:sp, PMID:19922875
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Washc2cpart_ofISOWASHC2C (Homo sapiens)1624291RGD PMID:19922875

PMID:19922875
Washc2cpart_ofISOWashc2 (Mus musculus)1624291RGD PMID:27390154

PMID:27390154
Washc2cpart_ofIEAUniProtKB:Q6PGL7 or ensembl:ENSMUSP000000389831600115EnsemblGO_REF:0000107

GO_REF:0000107
Washc2cpart_ofIBAFB:FBgn0034529 or MGI:106463 or PANTHER:PTN004553963 or UniProtKB:Q9Y4E1 or dictyBase:DDB_G02762211600115GO_CentralGO_REF:0000033

GO_REF:0000033
Washc2cpart_ofISSUniProtKB:Q9Y4E11600115UniProtGO_REF:0000024

GO_REF:0000024
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