GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sfrp2 | affects methylation | ISO | SFRP2 (Homo sapiens) | 6480464 | CTD | Decitabine affects the methylation of SFRP2 promoter | PMID:17848950 PMID:17882284 | Sfrp2 | decreases methylation | ISO | SFRP2 (Homo sapiens) | 6480464 | CTD | Decitabine results in decreased methylation of SFRP2 promoter | PMID:19387464 | Sfrp2 | increases expression | ISO | SFRP2 (Homo sapiens) | 6480464 | CTD | Decitabine results in increased expression of SFRP2 mRNA; Decitabine results in increased expression of SFRP2 protein | PMID:19387464 PMID:29320940 | Sfrp2 | increases methylation | ISO | SFRP2 (Homo sapiens) | 6480464 | CTD | Decitabine results in increased methylation of SFRP2 promoter | PMID:29320940 | Sfrp2 | multiple interactions | ISO | SFRP2 (Homo sapiens) | 6480464 | CTD | [Decitabine affects the methylation of SFRP2 promoter] which affects the expression of SFRP2 mRNA; [Decitabine affects the methylation of SFRP2 protein] which affects the expression of SFRP2 mRNA; [Decitabine affects the methylation of SFRP2 protein] which affects the expression of SFRP2 protein; [Decitabine co-treated with trichostatin A] results in increased expression of SFRP2 mRNA | PMID:17923031 PMID:18283316 PMID:18404682 | |
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