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GENE - TERM ANNOTATION REPORT

RGD ID: 735138
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tlr2
Name: toll-like receptor 2
Acc ID: GO:0002755
Term: MyD88-dependent toll-like receptor signaling pathway
Definition: A toll-like receptor signaling pathway in which the MyD88 adaptor molecule mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.
Definition Source(s): GOC:add, ISBN:0781735149, PMID:12467241, PMID:12524386, PMID:12855817, PMID:15585605, PMID:15728447
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tlr2acts_upstream_of_or_withinISOTlr2 (Mus musculus)1624291RGDMGI:108005 PMID:12719478

PMID:12719478
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