GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Myd88 | increases expression | ISO | MYD88 (Homo sapiens) | 6480464 | CTD | Paraquat results in increased expression of MYD88 protein | PMID:27890776 | Myd88 | increases expression | ISO | Myd88 (Mus musculus) | 6480464 | CTD | Paraquat results in increased expression of MYD88 mRNA; Paraquat results in increased expression of MYD88 protein | PMID:27890776 PMID:28012437 PMID:28131803 PMID:28363843 PMID:30584891 PMID:31299241 PMID:34811946 | Myd88 | increases response to substance | ISO | Myd88 (Mus musculus) | 6480464 | CTD | MYD88 protein results in increased susceptibility to Paraquat | PMID:28131803 | Myd88 | multiple interactions | ISO | MYD88 (Homo sapiens) | 6480464 | CTD | epigallocatechin gallate inhibits the reaction [Paraquat results in increased expression of MYD88 protein] | PMID:27890776 | Myd88 | multiple interactions | ISO | Myd88 (Mus musculus) | 6480464 | CTD | epigallocatechin gallate inhibits the reaction [Paraquat results in increased expression of MYD88 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Paraquat results in increased expression of MYD88 protein]; HSPD1 protein promotes the reaction [Paraquat results in increased expression of MYD88 protein]; MYD88 protein affects the reaction [Paraquat results in increased expression of IL1B mRNA]; MYD88 protein affects the reaction [Paraquat results in increased expression of IL1B protein]; MYD88 protein affects the reaction [Paraquat results in increased expression of TNF mRNA]; MYD88 protein affects the reaction [Paraquat results in increased expression of TNF protein]; MYD88 protein affects the reaction [Paraquat results in increased phosphorylation of RELA protein]; Paraquat inhibits the reaction [ST2825 results in decreased expression of MYD88 protein]; Phosphorothioate Oligonucleotides inhibits the reaction [Paraquat results in increased expression of MYD88 protein] | PMID:27890776 PMID:28131803 PMID:28363843 PMID:30584891 PMID:34811946 | | ||||||||||||||||||||||
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