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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735034
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Scin
Name: scinderin
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scindecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of SCIN mRNAPMID:33387578
Scinincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of SCIN mRNAPMID:34747641
Scinincreases expressionISOScin (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of SCIN mRNA; Tetrachlorodibenzodioxin results in increased expression of SCIN proteinPMID:11883943 PMID:16114106 PMID:17998272 PMID:20159946
Scinmultiple interactionsISOScin (Mus musculus)6480464CTDAHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of SCIN protein]PMID:11883943
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