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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734432
Species: Mus musculus
RGD Object: Gene
Symbol: Nfe2l2
Name: nuclear factor, erythroid derived 2, like 2
Acc ID: CHEBI:34887
Term: nickel dichloride
Definition: A compound of nickel and chloride in which the ratio of nickel (in the +2 oxidation state) to chloride is 1:2.
Chemical ID: MESH:C022838
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l2affects localizationISONFE2L2 (Homo sapiens)6480464CTDnickel chloride affects the localization of NFE2L2 proteinPMID:16806455
Nfe2l2increases expressionISONFE2L2 (Homo sapiens)6480464CTDnickel chloride results in increased expression of NFE2L2 proteinPMID:16806455 PMID:18437699
Nfe2l2multiple interactionsISONFE2L2 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [nickel chloride results in increased expression of NFE2L2 protein]; lipopolysaccharide A promotes the reaction [nickel chloride affects the localization of NFE2L2 protein]; Lipopolysaccharides promotes the reaction [nickel chloride results in increased expression of NFE2L2 protein]; nickel chloride promotes the reaction [lipopolysaccharide A results in increased expression of NFE2L2 protein]PMID:16806455 PMID:18437699
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