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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734432
Species: Mus musculus
RGD Object: Gene
Symbol: Nfe2l2
Name: nuclear factor, erythroid derived 2, like 2
Acc ID: CHEBI:30778
Term: gallic acid
Definition: A trihydroxybenzoic acid in which the hydroxy groups are at positions 3, 4, and 5.
Chemical ID: MESH:D005707
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l2multiple interactionsISONfe2l2 (Rattus norvegicus)6480464CTD[Gallic Acid co-treated with Dust] results in increased expression of NFE2L2 mRNA; Gallic Acid affects the reaction [[Dietary Fats co-treated with Dust] affects the expression of NFE2L2 mRNA]PMID:33953864 PMID:34745924
Nfe2l2multiple interactionsISONFE2L2 (Homo sapiens)6480464CTD[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] affects the localization of NFE2L2 protein; BMAL1 protein affects the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] affects the localization of NFE2L2 protein]; Gallic Acid inhibits the reaction [Ethanol results in decreased expression of NFE2L2 mRNA]; Gallic Acid inhibits the reaction [Ethanol results in decreased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [Gallic Acid inhibits the reaction [Ethanol results in increased activity of GPT protein]]; NFE2L2 protein affects the reaction [Gallic Acid inhibits the reaction [Ethanol results in increased expression of RIPK3 mRNA]]; NFE2L2 protein affects the reaction [Gallic Acid inhibits the reaction [Ethanol results in increased secretion of HMGB1 protein]]PMID:29061316 PMID:30853489
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