GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NFE2L2 | multiple interactions | EXP | | 6480464 | CTD | Potassium Dichromate inhibits the reaction [sodium arsenite promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; Potassium Dichromate inhibits the reaction [sodium arsenite results in increased localization of NFE2L2 protein] | PMID:16775837 | NFE2L2 | decreases response to substance | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | NFE2L2 protein results in decreased susceptibility to Potassium Dichromate | PMID:17420218 | NFE2L2 | increases activity | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | Potassium Dichromate results in increased activity of NFE2L2 protein | PMID:17420218 | NFE2L2 | increases expression | ISO | Nfe2l2 (Rattus norvegicus) | 6480464 | CTD | Potassium Dichromate results in increased expression of NFE2L2 protein | PMID:18548744 | NFE2L2 | multiple interactions | ISO | Nfe2l2 (Rattus norvegicus) | 6480464 | CTD | [Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of NFE2L2 mRNA; [Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of NFE2L2 protein; Plant Extracts promotes the reaction [Potassium Dichromate results in increased expression of NFE2L2 protein]; S-allylcysteine promotes the reaction [Potassium Dichromate results in increased expression of NFE2L2 protein] | PMID:18548744 PMID:36849043 | NFE2L2 | multiple interactions | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | [Potassium Dichromate affects the localization of and results in decreased ubiquitination of NFE2L2 protein] which results in increased expression of HMOX1 mRNA; [Potassium Dichromate affects the localization of and results in decreased ubiquitination of NFE2L2 protein] which results in increased expression of NQO1 mRNA; Potassium Dichromate affects the localization of and results in decreased ubiquitination of NFE2L2 protein; Potassium Dichromate inhibits the reaction [NFE2L2 protein binds to KEAP1 protein]; Potassium Dichromate promotes the reaction [NFE2L2 protein affects the abundance of Reactive Oxygen Species]; Potassium Dichromate promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer]; Potassium Dichromate promotes the reaction [NFE2L2 protein binds to NQO1 enhancer] | PMID:17420218 | | ||||||||||||||||||||||
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