GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NFE2L2 | increases activity | EXP | | 6480464 | CTD | Copper results in increased activity of NFE2L2 promoter | PMID:21643505 | NFE2L2 | multiple interactions | EXP | | 6480464 | CTD | [Chelating Agents binds to Copper] which affects the expression of NFE2L2 mRNA; [Chelating Agents binds to Copper] which results in increased expression of NFE2L2 mRNA; [Chitosan metabolite results in decreased susceptibility to Copper] which results in increased phosphorylation of NFE2L2 protein | PMID:25542178 PMID:30911355 | NFE2L2 | decreases response to substance | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | NFE2L2 gene results in decreased susceptibility to Copper | PMID:24462598 | NFE2L2 | increases localization | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | Copper results in increased localization of NFE2L2 protein | PMID:34676557 | NFE2L2 | multiple interactions | ISO | Nfe2l2 (Rattus norvegicus) | 6480464 | CTD | [Iron co-treated with Diethylnitrosamine co-treated with Copper] results in increased expression of NFE2L2 mRNA | PMID:20302851 | NFE2L2 | multiple interactions | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | NFE2L2 gene promotes the reaction [Copper results in increased expression of MT1 mRNA] | PMID:24462598 | | ||||||||||||||||||||||
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