GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NFE2L2 | increases localization | ISO | Nfe2l2 (Rattus norvegicus) | 6480464 | CTD | Hydrochloric Acid results in increased localization of NFE2L2 protein | PMID:18617559 | NFE2L2 | increases response to substance | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | NFE2L2 gene mutant form results in increased susceptibility to Hydrochloric Acid | PMID:29618784 | NFE2L2 | multiple interactions | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | [NFE2L2 gene mutant form results in increased susceptibility to Hydrochloric Acid] which results in increased expression of CAR3 mRNA; [NFE2L2 gene mutant form results in increased susceptibility to Hydrochloric Acid] which results in increased expression of HAVCR1 mRNA; [NFE2L2 gene mutant form results in increased susceptibility to Hydrochloric Acid] which results in increased expression of SLC38A1 mRNA; [NFE2L2 gene mutant form results in increased susceptibility to Hydrochloric Acid] which results in increased expression of SLC9A4 mRNA; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in decreased expression of SLC38A4 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in decreased expression of SLC3A2 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in decreased expression of SLC7A9 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of CYP2A5 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of DPYS mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of GCLC mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of GCLM mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of GSTA3 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of GSTM1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of NQO1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of SLC38A3 mRNA]; NFE2L2 protein promotes the reaction [Hydrochloric Acid results in increased expression of SLC38A3 mRNA] | PMID:29618784 | | ||||||||||||||||||||||
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