GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | JUN | increases expression | EXP | | 6480464 | CTD | Methotrexate results in increased expression of JUN | PMID:24444433 | JUN | increases phosphorylation | EXP | | 6480464 | CTD | Methotrexate results in increased phosphorylation of JUN protein | PMID:25327736 | JUN | increases expression | ISO | Jun (Rattus norvegicus) | 6480464 | CTD | Methotrexate results in increased expression of JUN protein | PMID:34737150 | JUN | multiple interactions | ISO | Jun (Rattus norvegicus) | 6480464 | CTD | Methotrexate inhibits the reaction [Freund's Adjuvant results in increased expression of JUN mRNA]; Perindopril inhibits the reaction [Methotrexate results in increased expression of JUN protein] | PMID:27613480 PMID:34737150 | |
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