GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | JUN | affects expression | ISO | Jun (Mus musculus) | 6480464 | CTD | Diethylnitrosamine affects the expression of JUN mRNA | PMID:21159647 | JUN | increases expression | ISO | Jun (Mus musculus) | 6480464 | CTD | Diethylnitrosamine results in increased expression of JUN mRNA; Diethylnitrosamine results in increased expression of JUN protein | PMID:10425313 PMID:18691550 PMID:19100860 | JUN | increases expression | ISO | Jun (Rattus norvegicus) | 6480464 | CTD | Diethylnitrosamine results in increased expression of JUN mRNA | PMID:25242409 | JUN | increases phosphorylation | ISO | Jun (Rattus norvegicus) | 6480464 | CTD | Diethylnitrosamine results in increased phosphorylation of JUN protein | PMID:19418558 | JUN | multiple interactions | ISO | Jun (Mus musculus) | 6480464 | CTD | [Diethylnitrosamine co-treated with Dietary Fats] affects the expression of JUN mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of JUN protein; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of JUN mRNA; [Piperonyl Butoxide co-treated with Diethylnitrosamine] results in increased expression of JUN mRNA; IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of JUN protein]; Limonene inhibits the reaction [Diethylnitrosamine results in increased expression of JUN protein]; MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of JUN mRNA] | PMID:10425313 PMID:18691550 PMID:18978307 PMID:19690152 PMID:30826251 | JUN | multiple interactions | ISO | Jun (Rattus norvegicus) | 6480464 | CTD | [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of JUN protein; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of JUN mRNA; Drugs, Chinese Herbal inhibits the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of JUN protein]; pyrazolanthrone inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of JUN protein] | PMID:17696247 PMID:19418558 PMID:22129741 | | ||||||||||||||||||||||
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