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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734356
Species: Homo sapiens
RGD Object: Gene
Symbol: JUN
Name: Jun proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:27563
Term: arsenic atom
Definition: A pnictogen that has formula As.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
JUNincreases expressionEXP 6480464CTDArsenic results in increased expression of JUN mRNAPMID:29248574 PMID:31739468
JUNmultiple interactionsEXP 6480464CTD[Arsenic co-treated with Iron] results in increased expression of JUN mRNA; [Palmitic Acid co-treated with Arsenic] results in increased expression of JUN mRNA; UCA1 mRNA promotes the reaction [Arsenic results in increased expression of JUN mRNA]PMID:29248574 PMID:31739468 PMID:33736254
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