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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734356
Species: Homo sapiens
RGD Object: Gene
Symbol: JUN
Name: Jun proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:17698
Term: chloramphenicol
Definition: An organochlorine compound that is dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and two alcohol functions.
Chemical ID: MESH:D002701
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
JUNmultiple interactionsEXP 6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Chloramphenicol results in increased phosphorylation of JUN protein]; Chloramphenicol results in increased phosphorylation of and affects the localization of JUN protein; pyrazolanthrone inhibits the reaction [Chloramphenicol results in increased phosphorylation of JUN protein]PMID:20338993
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