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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734300
Species: Mus musculus
RGD Object: Gene
Symbol: Bcl2l11
Name: BCL2 like 11
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2l11increases expressionEXP 6480464CTDEthanol results in increased expression of BCL2L11 mRNAPMID:24095927
Bcl2l11multiple interactionsISOBCL2L11 (Homo sapiens)6480464CTD[Ethanol co-treated with FOXO3 protein] results in increased expression of BCL2L11 mRNA; [Ethanol results in increased phosphorylation of FOXO3 protein] promotes the reaction [FOXO3 protein modified form binds to BCL2L11 gene]; Ethanol promotes the reaction [FOXO3 protein binds to BCL2L11 promoter]; Ethanol promotes the reaction [FOXO3 protein modified form binds to BCL2L11 gene]PMID:26470730
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