GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gpt | increases expression | EXP | | 6480464 | CTD | perfluorooctane sulfonic acid results in increased expression of GPT protein | PMID:34464680 PMID:35999056 | Gpt | multiple interactions | EXP | | 6480464 | CTD | [3,4,5,3',4'-pentachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased activity of GPT protein; [Dietary Fats co-treated with perfluorooctane sulfonic acid] results in increased expression of GPT protein; [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of GPT mRNA; [perfluorooctane sulfonic acid co-treated with Dietary Fats] results in increased expression of GPT protein; [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluorohexanesulfonic acid] inhibits the reaction [Dietary Fats results in increased expression of GPT protein]; Dietary Fats inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of GPT protein]; perfluorooctane sulfonic acid inhibits the reaction [Dietary Fats results in increased expression of GPT protein] | PMID:33096110 PMID:34464680 PMID:35999056 PMID:36331819 | Gpt | decreases expression | ISO | Gpt (Rattus norvegicus) | 6480464 | CTD | perfluorooctane sulfonic acid results in decreased expression of GPT mRNA | PMID:18692542 | | ||||||||||||||||||||||
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