GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gpt | increases activity | EXP | | 6480464 | CTD | Doxorubicin results in increased activity of GPT protein | PMID:25680506 | Gpt | increases expression | EXP | | 6480464 | CTD | Doxorubicin results in increased expression of GPT protein | PMID:36811345 PMID:37409694 | Gpt | multiple interactions | EXP | | 6480464 | CTD | [Doxorubicin co-treated with Hesperidin] results in decreased activity of GPT protein; BDKRB1 protein affects the reaction [Doxorubicin results in increased expression of GPT protein]; BDKRB2 protein affects the reaction [Doxorubicin results in increased expression of GPT protein]; naringin inhibits the reaction [Doxorubicin results in increased expression of GPT protein]; Silymarin inhibits the reaction [Doxorubicin results in increased expression of GPT protein] | PMID:29481770 PMID:36811345 PMID:37409694 | Gpt | increases activity | ISO | Gpt (Rattus norvegicus) | 6480464 | CTD | Doxorubicin results in increased activity of GPT protein | PMID:31100273 PMID:31830546 PMID:34343525 | Gpt | multiple interactions | ISO | Gpt (Rattus norvegicus) | 6480464 | CTD | chloroquine diphosphate promotes the reaction [Doxorubicin inhibits the reaction [Thioacetamide results in increased activity of GPT protein]]; Doxorubicin inhibits the reaction [Thioacetamide results in increased activity of GPT protein]; geraniol inhibits the reaction [Doxorubicin results in increased activity of GPT protein]; morin inhibits the reaction [Doxorubicin results in increased activity of GPT protein] | PMID:29133031 PMID:31100273 PMID:34343525 | |
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