GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gpt | multiple interactions | EXP | | 6480464 | CTD | [Arsenic co-treated with Fluorides] results in decreased activity of GPT protein | PMID:37482551 | Gpt | affects methylation | ISO | GPT (Homo sapiens) | 6480464 | CTD | Arsenic affects the methylation of GPT gene | PMID:25304211 | Gpt | increases activity | ISO | Gpt (Rattus norvegicus) | 6480464 | CTD | Arsenic results in increased activity of GPT protein | PMID:30324125 | Gpt | multiple interactions | ISO | Gpt (Rattus norvegicus) | 6480464 | CTD | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [Sodium Fluoride results in increased abundance of Fluorides]] results in decreased activity of GPT protein; [sodium arsenite results in increased abundance of Arsenic] which results in increased activity of GPT protein; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased activity of GPT protein]; Bosentan inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased activity of GPT protein]; Plant Extracts inhibits the reaction [Arsenic results in increased activity of GPT protein]; Succimer inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased activity of GPT protein] | PMID:30324125 PMID:32402895 PMID:33026618 PMID:33609566 | |
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