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GENE - TERM ANNOTATION REPORT

RGD ID: 734188
Species: Homo sapiens
RGD Object: Gene
Symbol: PTPN6
Name: protein tyrosine phosphatase non-receptor type 6
Acc ID: GO:0043409
Term: negative regulation of MAPK cascade
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade.
Definition Source(s): GOC:go_curators
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PTPN6involved_inIEAUniProtKB:P29351 or ensembl:ENSMUSP00000004377150520179Ensembl GO_REF:0000107
PTPN6acts_upstream_of_or_withinISOMGI:18560749068941MGI PMID:9064344 PMID:9254656

PMID:9064344 PMID:9254656
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