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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734172
Species: Homo sapiens
RGD Object: Gene
Symbol: CTSK
Name: cathepsin K
Acc ID: CHEBI:28819
Term: naringin
Definition: A disaccharide derivative that is (S)-naringenin substituted by a 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.
Chemical ID: MESH:C005274
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CTSKdecreases expressionISOCtsk (Mus musculus)6480464CTDnaringin results in decreased expression of CTSK mRNAPMID:24376342
CTSKmultiple interactionsISOCtsk (Mus musculus)6480464CTDnaringin inhibits the reaction [[TNFSF11 protein co-treated with CSF1R protein] results in increased expression of CTSK mRNA]PMID:21835177
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