GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp2c29 | decreases activity | EXP | | 6480464 | CTD | Quercetin results in decreased activity of CYP2C29 protein | PMID:18420780 | Cyp2c29 | decreases activity | ISO | CYP2C8 (Homo sapiens) | 6480464 | CTD | Quercetin results in decreased activity of CYP2C8 protein | PMID:15155557 PMID:15601807 PMID:29689254 | Cyp2c29 | multiple interactions | ISO | CYP2C8 (Homo sapiens) | 6480464 | CTD | [Quercetin results in decreased activity of CYP2C8 protein] which results in decreased degradation of vanoxerine; Quercetin inhibits the reaction [[CYP2C8 protein results in increased metabolism of Chloroquine] which results in increased abundance of desethylchloroquine]; Quercetin inhibits the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]; Quercetin inhibits the reaction [CYP2C8 protein results in increased metabolism of auriculasin] | PMID:11502731 PMID:12967198 PMID:24120545 PMID:31515991 | |
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