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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734119
Species: Mus musculus
RGD Object: Gene
Symbol: Mmp14
Name: matrix metallopeptidase 14 (membrane-inserted)
Acc ID: CHEBI:35807
Term: N-nitrosodimethylamine
Definition: A nitrosamine that has formula C2H6N2O.
Chemical ID: MESH:D004128
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp14increases expressionISOMmp14 (Rattus norvegicus)6480464CTDDimethylnitrosamine results in increased expression of MMP14 proteinPMID:18371158
Mmp14multiple interactionsISOMmp14 (Rattus norvegicus)6480464CTD[Dimethylnitrosamine co-treated with gadolinium chloride] results in increased expression of MMP14 mRNA; Drugs, Chinese Herbal inhibits the reaction [Dimethylnitrosamine results in increased expression of MMP14 protein]PMID:12493575 PMID:18371158
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