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GENE - TERM ANNOTATION REPORT

RGD ID: 734112
Species: Homo sapiens
RGD Object: Gene
Symbol: CLCN1
Name: chloride voltage-gated channel 1
Acc ID: GO:0005247
Term: voltage-gated chloride channel activity
Definition: Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
Definition Source(s): GOC:mtg_transport, ISBN:0815340729
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CLCN1 ISOClcn1 (Rattus norvegicus)9068941RGD PMID:1659664 REF_RGD_ID:727583
CLCN1enablesIBAMGI:105061 or PANTHER:PTN000189253 or Clcn1 (Rattus norvegicus) or Clcn2 (Rattus norvegicus) or UniProtKB:P35523 or UniProtKB:P51788 or WB:WBGene00000530150520179GO_Central GO_REF:0000033
CLCN1enablesIEAInterPro:IPR001807 or InterPro:IPR002243150520179InterPro GO_REF:0000002
CLCN1enablesIEAPANTHER:PTHR45720:SF4150520179TreeGrafter GO_REF:0000118
CLCN1enablesIMP 150520179UniProt PMID:22521272 PMID:26007199 PMID:26502825

PMID:22521272 PMID:26007199 PMID:26502825
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