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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734078
Species: Homo sapiens
RGD Object: Gene
Symbol: MGLL
Name: monoglyceride lipase
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MGLLdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of MGLL proteinPMID:31675489
MGLLdecreases methylationEXP 6480464CTDbisphenol A results in decreased methylation of MGLL genePMID:31601247
MGLLincreases expressionEXP 6480464CTDbisphenol A results in increased expression of MGLL proteinPMID:34186270
MGLLdecreases expressionISOMgll (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of MGLL mRNAPMID:25181051 PMID:30816183 PMID:34947998
MGLLdecreases expressionISOMgll (Mus musculus)6480464CTDbisphenol A results in decreased expression of MGLL mRNA; bisphenol A results in decreased expression of MGLL proteinPMID:33802611
MGLLincreases expressionISOMgll (Mus musculus)6480464CTDbisphenol A results in increased expression of MGLL mRNAPMID:32156529
MGLLincreases methylationISOMgll (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of MGLL genePMID:28505145
MGLLmultiple interactionsISOMgll (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of MGLL mRNAPMID:28433925
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