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GENE - TERM ANNOTATION REPORT

RGD ID: 733918
Species: Mus musculus
RGD Object: Gene
Symbol: Cacna1s
Name: calcium channel, voltage-dependent, L type, alpha 1S subunit
Acc ID: GO:0008331
Term: high voltage-gated calcium channel activity
Definition: Enables the transmembrane transfer of a calcium ion by a high voltage-gated channel. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded.
Definition Source(s): GOC:mtg_transport, ISBN:0815340729, PMID:16382099
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAMGI:MGI:88293, PANTHER:PTN000004694, RGD:2245, RGD:70973, RGD:70983, UniProtKB:O60840, UniProtKB:Q01668, UniProtKB:Q13698, UniProtKB:Q139362290270GO_Central (PMID:21873635)

PMID:21873635
 ISORGD:709832290270RGD GO_REF:0000096, MGI:MGI:4417868
 ISOUniProtKB:Q136982290270MGI GO_REF:0000096, MGI:MGI:4834177
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.