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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733897
Species: Homo sapiens
RGD Object: Gene
Symbol: TH
Name: tyrosine hydroxylase
Acc ID: CHEBI:3423
Term: carmustine
Definition: A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
Chemical ID: MESH:D002330
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
THincreases activityISOTh (Rattus norvegicus)6480464CTDCarmustine results in increased activity of TH proteinPMID:14670008
THincreases expressionISOTh (Rattus norvegicus)6480464CTDCarmustine results in increased expression of TH mRNA; Carmustine results in increased expression of TH proteinPMID:14670008
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